Kirsner炎症性肠疾病（第6版） Kirsner's Inflammatory Bowel Diseases 下载 pdf 百度网盘 epub 免费 2025 电子版 mobi 在线

　　This comprehensive New Edition describes all of the latest scientific and clinical advances in the field of inflammatory bowel disease (IBD). A new editorial teamjoined by a superb group of international authoritiesexamine every aspect of IBDincluding etiology and pathogenesis, diagnosis and evaluation, medical and surgical therapy, and more. A wealth of expanded coverage, additional international contributors, extensive updating throughout, and numerous diagnostic and therapeutic algorithms make this an essential resource.

Emphasizes evidence-based medicine in the section on medical therapy.

Features a detailed de*ion of inflammatory and immunologic pathways, allowing the reader to fully understand the contributing influences to the inflammation of IBD.

Presents separate chapters on molecular genetics and clinical genetics for more in-depth coverage of each aspect of inflammatory bowel disease genetics.

Provides a comprehensive review of IBD through abundant, high-quality endoscopic, radiographic, and histologic photographsplacing the various diagnostic modalities in perspective.

Offers extensive coverage of postoperative recurrence of Crohn's disease

· pouchitis

· microscopic colitis

· perianal disease

· and osteoporosis.

Includes up-to-the-minute guidance (including many 2003 references).

Features a new editorial team, joined by numerous new contributors who provide fresh, global perspectives.

Includes nine new chapters.

Offers expanded coverage throughout, and through revisions of all pre-existing chapters.

With over 75 additional contributing experts.

List of Contributors

Foreword

Preface

Section I　Mucosal protection and homeostasis

　1.Intestinal epithelia barrier function: characteristics and responses to neutrophil transepithelial migration

　2.Epithelial restitution and intestinal repair

　3.Epithelial-microbial interactions

　4.Immune cell-epithelial cell interactions

　5.The regulation of mucosal homeostasis and its relation to inflammatory bowel diseases

　6.T-lymphocyte trafficking

　7.Leukocyte, platelet and endothelial cell interactions in the inflammatory bowel diseases

Section II　Etiology and pathogenesis

　8.Genetics: molecular and chromosomal considerations

　9.Animal models of intestinal inflammation

　10.Microbial influences in inflammatory bowel diseases: role in pathogenesis and clinical implications

　11.Mechanisms of tissue injury

　12.Cytokines and inflammatory mediators

　13.T-lymphocyte dysregulation

　14.Neuroimmune interactions in the inflamed intestine

　15.Fibrogenesis

　16.Colorectal cancer in inflammatory bowel disease:molecular considerations

Section III　Epidemiology, clinical features and natural history

　17.Epidemiology of inflammatory bowel diseases

　18.Clinical genetics of inflammatory bowel diseases:genetic epidemiology, genotype-phenotype correlations and pharmacogenetics

　19.Clinical course and natural history of ulcerative colitis

　20.Clinical features and natural history of Crohn's disease

　21.Clinical features and natural history of pediatric inflammatory bowel diseases

　22.Physiologic consequences of surgical treatment for inflammatory bowel disease

　23.Fertility and pregnancy

　24.Psychosocial factors in ulcerative colitis and Crohn's disease

Section IV Diagnosis and evaluation

Section V Medical therapy

Section VI Surgical therapy

Section VII Complications and associated diseases

Index

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